jaelynev2789 jaelynev2789
  • 15-04-2021
  • Chemistry
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What molecules are affected by injury to the pancreas?

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alinasvapajej2121
alinasvapajej2121 alinasvapajej2121
  • 15-04-2021

Answer:

Causative/sensitizing factors of pancreatic injury include refluxed bile acids, alcohol, and pH. They largely mediate downstream events such as elevated intracellular Ca2+ via influx through TRPC3 channels and release from IP3 and ryanodine-sensitive Ca2+ stores.

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